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Journal of Robotics and Mechatronics

ISSN : 0915-3942(Print) / 1883-8049(Online)
Editor-in-Chief :Tatsuo Arai(Osaka University)
Deputy Editor-in-Chief :Kazuhiro Kosuge (Tohoku University), Kazunori Umeda (Chuo University)
Technically Co-sponsored by Robotics and Mechatronics Division of Japan Society of Mechanical Engineers

JRM Vol.19 No.5 Oct. 2007

System Cell Engineering by Multiscale Manipulation: Editors : Toshio Fukuda (Nagoya University, Japan) and Kenji Inoue (Yamagata University, Japan)

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JRM Vol.19 No.5 Oct. 2007

Editorial :

Special Issue on System Cell Engineering by Multiscale Manipulation

Toshio Fukuda and Kenji Inoue, pp. 499-499

Recent advancements in micro/nano robotics and mechatronics technology have contributed to the discovery of new scientific knowledge in bioscience and the development of new treatments and examinations in medical fields.

To promote interdisciplinary research among the engineering, biological, and medical fields and to promote further progress in these fields, Scientific Research on Priority Areas, "System Cell Engineering by Multiscale Manipulation (Head Investigator: Toshio Fukuda)," was begun in 2005. In this research area, we study system cell engineering seeking an understanding of communication and control principles of bare and integration functions of cells.
We focus on manipulation technology for work from nano- to macro-scale, i.e., multiscale manipulation. By controlling the local environment around a single cell, we actively induce chemical and physical interaction inside and outside the cell and measure changes.
We then work to clarify the mechanism behind the cell system and to realize an artificial cell model based on gene expression control and regenerate tissue by function control.
Using innovative engineering technology, we obtain new scientific knowledge in the life sciences and develop medical engineering, ultimately contributing to the good of society.

This special issue presents 2 reviews and 13 papers on the latest achievements in this research area. The reviews introduce challenging work in medical and biological fields, presenting suggestions on robotics and mechatronics engineers. Eight of the papers propose novel sensors, actuators, and other devices useful in bioscience and cell engineering. Two papers present methods of manipulating micro/nano-scale objects based on laser manipulation, and 2 concern the teleoperations of micro-hands and micro-manipulators for micromanipulation. The final paper discusses the interaction between living neuronal networks and the outer world.

We thank the authors for their invaluable contributions to this issue and the reviewers for their precious time and effort. We also thank the Editorial Board of JRM for making this issue possible.

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Review:: Grand Espoir: Robotics in Regenerative Medicine; Masayuki Yamato, Ryo Takagi, Makoto Kondo, Daisuke Murakami, Takeshi Ohki, \Hidekazu Sekine, Tatsuya Shimizu, Jun Kobayashi, Yoshikatsu Akiyama, Hideo Namiki, Masakazu Yamamoto, and Teruo Okano, pp. 500-505; Abstract | Preview | Full Text (PDF182KB)
Review:: Tooth Regenerative Therapy, Approached from Organogenesis; Kazuhisa Nakao, and Takashi Tsuji,, pp. 506-511; Abstract | Preview | Full Text (PDF598KB)
Paper:: Fabrication of FIB-CVD Nanotemperature Sensor Probe for Local Temperature Sensing in Water Environments; Haitham ElShimy, Masahiro Nakajima, Yoshiaki Imaizumi, Fumihito Arai, and Toshio Fukuda, pp. 512-518; Abstract | Preview | Full Text (PDF371KB)
Paper:: Multiscale 2D-SPR Biosensing for Cell Chips; Masayasu Suzuki, Toyohiro Ohshima, Shintaro Hane, Yasunori Iribe, and Tatsuya Tobita, pp. 519-523; Abstract | Preview | Full Text (PDF321KB)
Paper:: Liquid Crystal Actuator Using Nematic π-Cell; Yoshitaka Mieda and Katsushi Furutani, pp. 524-527; Abstract | Preview | Full Text (PDF320KB)

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Paper:: Development of Novel Nanopipette with a Lipid Nanotube as Nanochannel; Kousuke Nogawa, Yusuke Tagawa, Masahiro Nakajima, Fumihito Arai, Toshimi Shimizu, Shoko Kamiya, and Toshio Fukuda, pp. 528-534; Abstract | Preview | Full Text (PDF457KB)
Paper:: Fabrication of Cell-Adhesion Surface and Arteriole Modelby Photolithography; Fumihito Arai, Takuma Nakano, Mika Tada, Yu-Ching Lin, Seiichi Ikeda, Tomoyuki Uchida, Hiroyuki Oura, Toshio Fukuda, Takehisa Matsuda, and Makoto Negoro, pp. 535-543; Abstract | Preview | Full Text (PDF843KB)
Paper:: Development of a Multi-Compartment Micro-Cell Culture Device as a Future On-Chip Human: Fabrication of a Three-Compartment Device and Immobilization of Mature Rat Adipocytes for the Evaluation of Chemical Distributions; Hidenari Nakayama, Hiroshi Kimura, Kikuo Komori, Teruo Fujii, and Yasuyuki Sakai,, pp. 544-549; Abstract | Preview | Full Text (PDF719KB)
Paper:: Microfluidic Perfusion Culture of Human Hepatocytes; Hiroshi Kimura, Masaki Nishikawa, Takatoki Yamamoto, Yasuyuki Sakai, and Teruo Fujii, pp. 550-556; Abstract | Preview | Full Text (PDF413KB)
Paper:: Effect of Mechanical Environment of Focal Adhesions on Remodeling of Endothelial Cells Subjected to Cyclic Stretching Using Microsubstrates; Naoya Sakamoto, Yoshimasa Yamazaki, Toshiro Ohashi, and Masaaki Sato, pp. 557-564; Abstract | Preview | Full Text (PDF591KB)

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Paper:: Optically Driven Micromanipulators with Rotating Arms; Shoji Maruo, and Yojiro Hiratsuka, pp. 565-568; Abstract | Preview | Full Text (PDF386KB)
Paper:: In-Situ Formation of a Gel Microbead for Laser Micromanipulation of Microorganisms, DNA, and Viruses; Akihiko Ichikawa, Ayae Honda, Miho Ejima, Tamio Tanikawa, Fumihito Arai, and Toshio Fukuda, pp. 569-576; Abstract | Preview | Full Text (PDF706KB)
Paper:: Performance Evaluation of Teleoperation for Manipulating Micro Objects Using Two-Fingered Micro Hand; Kenji Inoue, Daisuke Nishi, Tomohito Takubo, Tamio Tanikawa, and Tatsuo Arai, pp. 577-584; Abstract | Preview | Full Text (PDF345KB)
Paper:: Versatile Robotic Biomanipulation with Haptic Interface; Gilgueng Hwang, Preeda Chantanakajornfung, and Hideki Hashimoto, pp. 585-591; Abstract | Preview | Full Text (PDF1545KB)
Paper:: Biomodeling System -- Interaction Between Living Neuronal Networks and the Outer World; Suguru N. Kudoh, Chie Hosokawa, Ai Kiyohara, Takahisa Taguchi, and Isao Hayashi, pp. 592-600; Abstract | Preview | Full Text (PDF669KB)

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