JRM Vol.28 No.6 pp. 854-861
doi: 10.20965/jrm.2016.p0854


Vision-Based Real-Time Microflow-Rate Control System for Cell Analysis

Tadayoshi Aoyama, Amalka De Zoysa, Qingyi Gu, Takeshi Takaki, and Idaku Ishii

Department of System Cybernetics, Hiroshima University
1-4-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8527, Japan

April 24, 2016
September 18, 2016
December 20, 2016
LOC, microparticle sorting system, visual feedback control

Vision-Based Real-Time Microflow-Rate Control System for Cell Analysis

Snapshots of particle sorting experiment using our system

On-chip cell analysis is an important issue for microtechnology research, and microfluidic devices are frequently used in on-chip cell analysis systems. One approach to controlling the fluid flow in microfluidic devices for cell analysis is to use a suitable pumps. However, it is difficult to control the actual flow-rate in a microfluidic device because of the difficulty in placing flow-rate sensors in the device. In this study, we developed a real-time flow-rate control system that uses syringe pumps and high-speed vision to measure the actual fluid flow in microfluidic devices. The developed flow-rate control system was verified through experiments on microparticle velocity control and microparticle sorting.

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Last updated on Sep. 20, 2017