Verification of Single-Molecule Imaging and Single-Molecule Measurements
Akihiko Ishijima, Hajime Fukuoka, and Yuichi Inoue
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan
Single-molecule imaging and single-molecule measurements constitute an integral part of life science researches. The research method, which allows direct measurements of individual motions and events of biomolecules, has contributed much to the development of life science research by providing us with numerous findings. It is left up to the judgment of researchers, however, whether the measurements really represent single-molecule events, which make it harder for more researchers to enter into this field. This paper deals with how single-molecule measurements were presented in past research outcomes and illustrates statistical-mechanical methods as well.
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