JRM Vol.22 No.5 pp. 568-578
doi: 10.20965/jrm.2010.p0568


Verification of Single-Molecule Imaging and Single-Molecule Measurements

Akihiko Ishijima, Hajime Fukuoka, and Yuichi Inoue

Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan

May 24, 2010
June 22, 2010
October 20, 2010
single-molecule imaging, single-molecule measurement, evanescence, Poisson distribution, molecular motor
Single-molecule imaging and single-molecule measurements constitute an integral part of life science researches. The research method, which allows direct measurements of individual motions and events of biomolecules, has contributed much to the development of life science research by providing us with numerous findings. It is left up to the judgment of researchers, however, whether the measurements really represent single-molecule events, which make it harder for more researchers to enter into this field. This paper deals with how single-molecule measurements were presented in past research outcomes and illustrates statistical-mechanical methods as well.
Cite this article as:
A. Ishijima, H. Fukuoka, and Y. Inoue, “Verification of Single-Molecule Imaging and Single-Molecule Measurements,” J. Robot. Mechatron., Vol.22 No.5, pp. 568-578, 2010.
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