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JRM Vol.17 No.3 pp. 318-326
doi: 10.20965/jrm.2005.p0318
(2005)

Paper:

A Dynamic Body Model of the Nematode C. elegans with Neural Oscillators

Michiyo Suzuki*, Takeshi Goto*, Toshio Tsuji*,
and Hisao Ohtake**

*Department of Artificial Complex Systems Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8527, Japan

**Department of Biotechnology, Osaka University, 2-1 Yamadaoka, Suita-shi, Osaka 565-0871, Japan

Received:
October 17, 2004
Accepted:
May 10, 2005
Published:
June 20, 2005
Keywords:
C. elegans, neural circuit model, dynamic body model, neural oscillator, computer simulation
Abstract

The nematode Caenorhabditis elegans (C. elegans), a relatively simple organism in structure, is one of the most well-studied multicellular organisms. We developed a virtual C. elegans based on the actual organism to analyze motor control. We propose a dynamic body model, including muscles, controlled by a neural circuit model based on the actual nematode. The model uses neural oscillators to generate rhythmic movement. Computer simulation confirmed that the virtual C. elegans realizes motor control similar qualitatively to that of the actual organism. Specified classes of neurons are killed in the neural circuit model corresponding to actual unc mutants, demonstrating that resulting movement of the virtual C. elegans resembles that of actual mutants.

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Last updated on Jun. 28, 2017