Protein Structural Class Prediction via k-Separated Bigrams Using Position Specific Scoring Matrix
Harsh Saini*, Gaurav Raicar*, Alok Sharma*,**,
Sunil Lal*, Abdollah Dehzangi**, Rajeshkannan Ananthanarayanan*,
James Lyons**, Neela Biswas***, and Kuldip K. Paliwal**
*The University of the South Pacific, Fiji, Laucala Bay, Suva, Fiji
**Griffith University, Brisbane, Australia
***Royal Brisbane and Women’s Hospital, Brisbane, Australia
Protein structural class prediction (SCP) is as important task in identifying protein tertiary structure and protein functions. In this study, we propose a feature extraction technique to predict secondary structures. The technique utilizes bigram (of adjacent and k-separated amino acids) information derived from Position Specific Scoring Matrix (PSSM). The technique has shown promising results when evaluated on benchmarked Ding and Dubchak dataset.
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