The 2010 International Symposium on Intelligent Systems (iFAN2010) was held at Tokyo Metropolitan University, Tokyo, Japan, in September 2010, in conjunction with the 20th anniversary of the 2010 Intelligent System Symposium (FAN2010). These two symposiums provided a fine opportunity for researchers to exchange ideas on basic theories and applications on intelligent systems and iFAN2010 was the first international symposium in the history of the FAN symposium.

From more than 200 papers of FAN2010 and iFAN2010, papers of top quality were invited to this special issue. From 17 papers submitted, 13 outstanding papers have been selected for this special issue after fair and peer review process. As these two symposiums covered a wide variety of intelligence-related issues, this special issue also consists of various topics from basic theories such as machine learning, adaptive control, and optimization, to application-oriented studies such as medical image processing, human support systems, and land mine detection. This issue is expected to contribute much to research on intelligent systems.

As the Editors of this special issue, we thank the contributors and reviewers for their time and cooperation. We look forward to actively participating to the next FAN2011, to be held at Kobe University, Hyogo, Japan, in September 2011, which we hope will be as successful and fruitful as the 2010 symposium.