Fabrication of Microneedle Mimicking Mosquito Proboscis Using Nanoscale 3D Laser Lithography System
Masato Suzuki, Takahiro Sawa, Tomokazu Takahashi, and Seiji Aoyagi
3-3-35 Yamate-cho, Suita, Osaka 564-8680, Japan
A mosquito’s proboscis, which is used for sucking blood, consists of seven complicated parts. For example, the labrum has a hollow structure, and the maxillae have micrometer-sized tooth like projections on its tip. In this study, microneedles imitating one labium and two maxillae were fabricated using a precision three-dimensional laser lithography system “Nanoscribe.” The maximum length of the fabricated microneedle was 2.0 mm, the minimum length required to reach human capillary blood vessel underneath the epidermis.
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