This paper describes expectations for Transdisciplinary Federation of Science and Technology viewed from manufacturing industry. Challenges of manufacturing industry in terms of transdisciplinary technology are presented ranging from problem oriented approaches to design methodology, and some preliminary practices are demonstrated including visualization by sensor network and analysis-led design. Manufacturing industry has been starting integration of diversified knowledge in order to respond to real world requirements, but the integration experiences are scarcely reusable. For better transformation of the integration experiences to reusable knowledge, which is one of the essential values of transdisciplinary technology, collaboration of academia, government, and industry in real situations is strongly desired as well as providing appropriate education for knowledge integration at universities.