Chien-Cheng Lee, Sz-Han Chen, and Yu-Chun Chiang

Abstract:
We propose a classifier based on the support vector machine (SVM) for automatic classification in liver disease. The SVM, stemming from statistical learning theory, involves state-of-the-art machine learning. The classifier is a part of computer-aided diagnosis (CADx), which assists radiologists in accurately diagnosing liver disease. We formulate discriminating between cysts, hepatoma, cavernous hemangioma, and normal tissue as a supervised learning problem, and apply SVM to classifying the diseases using gray level and co-occurrence matrix features and region-based shape descriptors, calculated from regions of interest (ROIs), as input. Significant features of ROI enable us to simplify SVM input space and to feed the SVM representative information. By simplifying and clarifying the diagnosis process, we separate the classification of liver disease into hierarchical multiclass classification. We use the receiver operating characteristic (ROC) curve to evaluate diagnosis performance, demonstrating the classifier's good performance.

Keywords: SVM, co-occurrence matrix, liver cyst, hepatoma, hemangioma